Big Ten and other biggest college football game expert picks and predictions for Week 13

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Big Ten and other biggest college football game expert picks and predictions for Week 13

It's tradition now. Every year (and every week of the season), we have a little friendly competition among our writers for world domination when it comes to picking the Big Ten football games and some of the bigger college football contests throughout the season, now that conference play is in full swing.

With just a couple of weeks left in the regular season, Ohio State, Oregon, and Indiana are getting a lot of national notoriety and seem to be the three teams contending for league superiority. However, you can't count out USC and Michigan, who also have just one loss in the conference, and hope to have something to say about it all. And Penn State … well — that's another story for another day.

So, just how will Week 13 play out in the Big Ten? Our writers take turns picking all the games in the conference straight up and against the spread for your wagering and reading consumption — do with it as you wish.

As a reminder, if there’s an asterisk next to the pick, that means the team will win, but not cover. If there is a tie, rather than have a cage match or old-fashioned duel, we’ll settle it with less violence and go with the tried, yet true, coin flip, where George Washington has the say.

EXAMPLE: If Ohio State is favored -3.5 over Michigan:

If you think Ohio State will win outright and cover: OSU

If you think Ohio State will win, but NOT cover: OSU*

If you think Ohio State will lose: Michigan

Here are our expert picks for Week 13 as things get deeper into conference play and we head towards the home stretch of the regular season. We throw in the top five non-Big Ten games as well to make it more interesting.

Standings so far

Follow Phil Harrison: 125-32 SU, 83-74 ATS

Follow MarkRussell: 124-33 SU, 79-78 ATS

Follow Griffin Dreifeldt: 129-28 SU, 88-69 ATS

Follow Yesh Ginsburg: 120-37 SU, 91-66 ATS

CONSENSUS PICK: 127-30 SU, 91-66 ATS

First up … Big Ten games

Rutgers at Ohio State

Nov 15, 2025; Columbus, Ohio, USA; Ohio State Buckeyes mascot Brutus Buckeye fires up the crowd during the second quarter against the UCLA Bruins at Ohio Stadium. Mandatory Credit: Joseph Maiorana-Imagn Images

Saturday, Nov. 22

Noon p.m. ET | Fox (Stream fuboTV (watch here))

Betting Line | Ohio State -31.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Ohio State*

Mark Russell (@MarkRussell1975) | Ohio State*

Griffin Dreifaldt (@griffin_drei) | Ohio State

Yesh Ginsburg (@yesh222) | Ohio State*

CONSENSUS PICK | Ohio State*

Minnesota at Northwestern

Aug 30, 2025; New Orleans, Louisiana, USA; Northwestern Wildcats quarterback Preston Stone (8) passes against Tulane Green Wave during the second half at Yulman Stadium. Mandatory Credit: Stephen Lew-Imagn Images

Saturday, Nov. 22

Noon ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Northwestern -3.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Northwestern

Mark Russell (@MarkRussell1975) | Minnesota

Griffin Dreifaldt (@griffin_drei) | Northwestern

Yesh Ginsburg (@yesh222) | Northwestern

CONSENSUS PICK | Northwestern

USC at Oregon

Oct 25, 2025; Eugene, Oregon, USA; Oregon Ducks offensive lineman Alex Harkey (71) celebrates after a touchdown during the second half against the Wisconsin Badgers at Autzen Stadium. Mandatory Credit: Troy Wayrynen-Imagn Images

Saturday, Nov. 22

3:30 p.m. ET | CBS (Stream fuboTV (watch here))

Betting Line | Oregon -9.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Oregon

Mark Russell (@MarkRussell1975) | Oregon*

Griffin Dreifaldt (@griffin_drei) | Oregon*

Yesh Ginsburg (@yesh222) | Oregon*

CONSENSUS PICK: Oregon*

Michigan State at Iowa

Nov 15, 2025; Los Angeles, California, USA; Iowa Hawkeyes wide receiver Dayton Howard (7) celebrates his touchdown scored against the Southern California Trojans during the first half at the Los Angeles Memorial Coliseum. Mandatory Credit: Gary A. Vasquez-Imagn Images

Saturday, Nov. 22

3:30 p.m. ET | FS1 (Stream fuboTV (watch here))

Betting Line | Iowa -16.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Iowa*

Mark Russell (@MarkRussell1975) | Iowa

Griffin Dreifaldt (@griffin_drei) | Iowa

Yesh Ginsburg (@yesh222) | Iowa

CONSENSUS PICK | Iowa

Michigan at Maryland

Aug 31, 2024; College Park, Maryland, USA; Maryland Terrapins quarterback Billy Edwards Jr. (9) signals to a receiver during the second quarter against the Connecticut Huskies at SECU Stadium. Mandatory Credit: Daniel Kucin Jr.-USA TODAY Sports

Saturday, Nov. 22

4:00 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Michigan -13.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Michigan

Mark Russell (@MarkRussell1975) | Michigan

Griffin Dreifaldt (@griffin_drei) | Michigan*

Yesh Ginsburg (@yesh222) | Michigan*

CONSENSUS PICK | Michigan

Nebraska at Penn State

Penn State Nittany Lions interim head coach Terry Smith in the first half of the college football game at Ohio Stadium on Saturday, Nov. 1, 2025 in Columbus, Ohio.

Saturday, Nov. 22

7:30 p.m. ET | NBC (Stream fuboTV (watch here))

Betting Line | Penn State -8.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Penn State

Mark Russell (@MarkRussell1975) | Penn State

Griffin Dreifaldt (@griffin_drei) | Penn State

Yesh Ginsburg (@yesh222) | Nebraska

CONSENSUS PICK | Penn State

Illinois at Wisconsin

Oct 18, 2025; Madison, Wisconsin, USA; Wisconsin Badgers head coach Luke Fickell looks on in the second half against the Ohio State Buckeyes at Camp Randall Stadium. Mandatory Credit: Jeff Hanisch-Imagn Images

Saturday, Nov. 22

7:30 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Illinois -7.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Illinois

Mark Russell (@MarkRussell1975) | Illinois

Griffin Dreifaldt (@griffin_drei) | Illinois

Yesh Ginsburg (@yesh222) | Illinois

CONSENSUS PICK | Illinois

Washington at UCLA

Aug 30, 2025; Pasadena, California, USA; UCLA Bruins quarterback Nico Iamaleava (9) following the loss against the Utah Utes during the second half at Rose Bowl. Mandatory Credit: Gary A. Vasquez-Imagn Images

Saturday, Nov. 22

10:30 p.m. ET | NBC (Stream fuboTV (watch here))

Betting Line | Washington -10.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Washington

Mark Russell (@MarkRussell1975) | Washington

Griffin Dreifaldt (@griffin_drei) | Washington

Yesh Ginsburg (@yesh222) | Washington

CONSENSUS PICK | Washington

Next … 5 biggest non-Big Ten games

Missouri at Oklahoma

Oklahoma's Sammy Omosigho (7) celebrates a play in the second half of the college football game between the University of Oklahoma Sooner and the University of Michigan Wolverines at the Gaylord Family Ð Oklahoma Memorial Stadium in Norman, Okla., Saturday, Sept. 6, 2025.

Saturday, Nov. 22

Noon ET | ABC (Stream fuboTV (watch here))

Betting Line | Oklahoma -7.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Oklahoma

Mark Russell (@MarkRussell1975) | Oklahoma*

Griffin Dreifaldt (@griffin_drei) | Oklahoma*

Yesh Ginsburg (@yesh222) | Oklahoma

CONSENSUS PICK | Oklahoma

Miami (FL) at Virginia Tech

Oct 17, 2025; Miami Gardens, Florida, USA; Miami Hurricanes quarterback Carson Beck (11) looks for a passing option against the Louisville Cardinals during the third quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images

Saturday, Nov. 22

Noon ET | ESPN (Stream fuboTV (watch here))

Betting Line | Miami -17.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Miami

Mark Russell (@MarkRussell1975) | Miami

Griffin Dreifaldt (@griffin_drei) | Miami

Yesh Ginsburg (@yesh222) | Miami*

CONSENSUS PICK | Miami

Syracuse at Notre Dame

Notre Dame wide receiver Jerome Bettis Jr. (15), cornerback Cree Thomas (20) and others celebrate after winning a NCAA football game 49-10 against Navy at Notre Dame Stadium on Saturday, Nov. 8, 2025, in South Bend.

Saturday, Nov. 22

3:30 p.m. ET | NBC (Stream fuboTV (watch here))

Betting Line | Notre Dame -35.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Notre Dame*

Mark Russell (@MarkRussell1975) | Notre Dame*

Griffin Dreifaldt (@griffin_drei) | Notre Dame

Yesh Ginsburg (@yesh222) | Notre Dame*

CONSENSUS PICK | Notre Dame*

Arkansas at Texas

Nov 1, 2025; Austin, Texas, USA; Texas Longhorns quarterback Arch Manning (16) throws a pass during the first half against the Vanderbilt Commodores at Darrell K Royal-Texas Memorial Stadium. Mandatory Credit: Scott Wachter-Imagn Images

Saturday, Nov. 22

3:30 p.m. ET | ABC (Stream fuboTV (watch here))

Betting Line | Texas -9

The Picks:

Phil Harrison (@PhilHarrisonBW) | Texas

Mark Russell (@MarkRussell1975) | Texas

Griffin Dreifaldt (@griffin_drei) | Texas

Yesh Ginsburg (@yesh222) | Texas

CONSENSUS PICK | Texas

Tennessee at Florida

Sep 15, 2007; Gainesville, FL, USA; Florida Gators quarterback Tim Tebow (15) celebrates after a 59-20 win against the Tennessee Volunteers at Ben Hill Griffin Stadium in Gainesville, FL. Mandatory Credit: Jason Parkhurst-USA TODAY Sports Copyright © 2007 Jason Parkhurst

Saturday, Nov. 22

7:30 p.m. ET | ABC (Stream fuboTV (watch here))

Betting Line | Tennessee -4.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Florida

Mark Russell (@MarkRussell1975) | Tennessee

Griffin Dreifaldt (@griffin_drei) | Florida

Yesh Ginsburg (@yesh222) | Florida

CONSENSUS PICK | Florida

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This article originally appeared on Buckeyes Wire: Big Ten football picks and predictions: Experts weigh in for Week 13

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