College GameDay picks Week 5's biggest games

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Week 5 of the college football season is here, and ESPN's premier preview show is back to pick college football's most intriguing games.

This week, "College GameDay" was in Iowa City, Iowa, for the top-25 Big Ten showdown between the No. 14 Iowa Hawkeyes and the No. 6 Ohio State Buckeyes at Kinnick Stadium. Saturday was the 3rd time College GameDay has originated from the University of Iowa, and the first time since Sept. 30, 2006, when the Hawkeyes hosted Ohio State.

This week, the usual lineup of Rece Davis, Kirk Herbstreit, Desmond Howard, Pat McAfee, and former Alabama head coach Nick Saban made their picks for this week's biggest games, with Caitlin Clark serving as this week's celebrity guest picker.

Clark won the Big Ten Player of the Year award three times as a point guard for the Iowa Hawkeyes after averaging 28.4 points, 8.2 assists, and 7.1 rebounds per game over her four-year career from 2020-24. She later became the No. 1 overall pick in the 2024 WNBA Draft and is now one of the league's most recognizable faces with the Indiana Fever.

How did the College Gameday crew forecast this week's top games? Here's a look at this week's picks for Week 5 of the college football season.

West Virginia at Iowa State

Desmond Howard: Iowa State
Nick Saban: West Virginia
Pat McAfee: West Virginia
Kirk Herbstreit: West Virginia
Caitlin Clark: Iowa State

Eastern Michigan at UMass

Desmond Howard: UMass
Nick Saban: UMass
Pat McAfee: UMass
Kirk Herbstreit: UMass
Caitlin Clark: UMass

BYU at TCU

Desmond Howard: BYU
Nick Saban: BYU
Pat McAfee: BYU
Kirk Herbstreit: BYU
Caitlin Clark: BYU

Cincinnati at Arizona

Desmond Howard: Arizona
Nick Saban: Arizona
Pat McAfee: Cincinnati
Kirk Herbstreit: Cincinnati
Caitlin Clark: Arizona

Miami at Clemson

Desmond Howard: Miami
Nick Saban: Miami
Pat McAfee: Miami
Kirk Herbstreit: No pick due to calling the game on ABC
Caitlin Clark: Miami

Washington at USC

Desmond Howard: USC
Nick Saban: USC
Pat McAfee: USC
Kirk Herbstreit: Washington
Caitlin Clark: USC

Michigan at Minnesota

Desmond Howard: Michigan
Nick Saban: Michigan
Pat McAfee: Michigan
Kirk Herbstreit: Minnesota
Caitlin Clark: Michigan

Alabama at Mississippi State

Desmond Howard: Mississippi State
Nick Saban: Alabama
Pat McAfee: Alabama
Kirk Herbstreit: Alabama
Caitlin Clark: Mississippi State

Florida at Missouri

Desmond Howard: Florida
Nick Saban: Florida
Pat McAfee: Florida
Kirk Herbstreit: Florida
Caitlin Clark: Florida

Ohio State at Iowa

Desmond Howard: Iowa
Nick Saban: Ohio State
Pat McAfee: Ohio State
Kirk Herbstreit: Ohio State
Caitlin Clark: Iowa

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This article originally appeared on Auburn Wire: College GameDay picks Week 5's biggest games

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