Big Ten and other biggest college football game expert picks and predictions for Week 11

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Big Ten and other biggest college football game expert picks and predictions for Week 11

It's tradition now. Every year (and every week of the season), we have a little friendly competition among our writers for world domination when it comes to picking the Big Ten football games and some of the bigger college football contests throughout the season once conference play gets into full swing.

Though we never really know, Ohio State, Oregon, and Indiana are getting a lot of national notoriety and seem to be the three teams contending for league superiority. However, you can't count out teams like USC, Michigan, and Iowa, who also have just one loss in the conference and hope to have something to say about it all. And Penn State … well — that's another story for another day.

So, just how will Week 11 play out in the Big Ten? Our writers take turns picking all the games in the conference straight up and against the spread for your wagering and reading consumption — do with it as you wish.

As a reminder, if there’s an asterisk next to the pick, that means the team will win, but not cover. If there is a tie, rather than have a cage match or old-fashioned duel, we’ll settle it with less violence and go with the tried, yet true, coin flip, where George Washington has the say.

EXAMPLE: If Ohio State is favored -3.5 over Michigan:

If you think Ohio State will win outright and cover: OSU

If you think Ohio State will win, but NOT cover: OSU*

If you think Ohio State will lose: Michigan

Here are our expert picks for Week 11 as things get deeper into conference play and we head towards the home stretch of the regular season. We throw in the top five non-Big Ten games as well to make it more interesting.

Standings so far

Follow Phil Harrison: 106-26 SU, 68-64 ATS

Follow MarkRussell: 105-27 SU, 65-67 ATS

Follow Griffin Dreifeldt: 110-22 SU, 78-54 ATS

Follow Yesh Ginsburg: 99-33 SU, 78-54 ATS

CONSENSUS PICK: 108-24 SU, 78-54 ATS

First up … Big Ten games

Northwestern at USC

Aug 30, 2025; Los Angeles, California, USA; Southern California Trojans head coach Lincoln Riley gestures during the game against the Missouri State Bears at United Airlines Field at Los Angeles Memorial Coliseum. Mandatory Credit: Kirby Lee-Imagn Images

Friday, Nov. 7

9:00 p.m. ET | Fox (Stream fuboTV (watch here))

Betting Line | USC -14.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | USC

Mark Russell (@MarkRussell1975) | USC

Griffin Dreifaldt (@griffin_drei) | USC

Yesh Ginsburg (@yesh222) | USC

CONSENSUS PICK | USC

Indiana at Penn State

Sep 20, 2025; Bloomington, Indiana, USA; Indiana Hoosiers head coach Curt Cignetti watches his team during the second half against the Illinois Fighting Illini at Memorial Stadium. Mandatory Credit: Robert Goddin-Imagn Images

Saturday, Nov. 8

Noon ET | Fox (Stream fuboTV (watch here))

Betting Line | Indiana -14.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Indiana

Mark Russell (@MarkRussell1975) | Indiana

Griffin Dreifaldt (@griffin_drei) | Indiana

Yesh Ginsburg (@yesh222) | Indiana

CONSENSUS PICK | Indiana

Ohio State at Purdue

Nov 1, 2025; Columbus, Ohio, USA; Ohio State Buckeyes wide receiver Carnell Tate (17) dives in for a touchdown as Penn State Nittany Lions cornerback Zion Tracy (7) misses the tackle during the second quarter at Ohio Stadium. Mandatory Credit: Joseph Maiorana-Imagn Images

Saturday, Nov. 8

1:00 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Ohio State -29.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Ohio State*

Mark Russell (@MarkRussell1975) | Ohio State

Griffin Dreifaldt (@griffin_drei) | Ohio State*

Yesh Ginsburg (@yesh222) | Ohio State

CONSENSUS PICK: Ohio State

Maryland at Rutgers

Rutgers Head Coach, Greg Schiano watches his Scarlet Knights, Thursday, August 28, 2025.

Saturday, Nov. 8

2:30 p.m. ET | FS1 (Stream fuboTV (watch here))

Betting Line | Maryland -1.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Maryland

Mark Russell (@MarkRussell1975) | Maryland

Griffin Dreifaldt (@griffin_drei) | Maryland

Yesh Ginsburg (@yesh222) | Rutgers

CONSENSUS PICK | Maryland

Oregon at Iowa

27 years: Kirk Ferentz has been Iowa's head coach since 1999 with a 210-126 record (.625) and 22 bowl appearances.

Saturday, Nov. 8

3:30 p.m. ET | CBS (Stream fuboTV (watch here))

Betting Line | Oregon -6

The Picks:

Phil Harrison (@PhilHarrisonBW) | Oregon*

Mark Russell (@MarkRussell1975) | Iowa

Griffin Dreifaldt (@griffin_drei) | Oregon

Yesh Ginsburg (@yesh222) | Iowa

CONSENSUS PICK | Oregon

Washington at Wisconsin

Oct 18, 2025; Madison, Wisconsin, USA; Wisconsin head coach Luke Fickell reacts after Ohio State missed a field goal during the second quarter at Camp Randall Stadium.

Saturday, Nov. 8

4:30 p.m. ET | Big Ten Network (Stream fuboTV (watch here))

Betting Line | Washington -11.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Washington*

Mark Russell (@MarkRussell1975) | Washington

Griffin Dreifaldt (@griffin_drei) | Washington

Yesh Ginsburg (@yesh222) | Washington

CONSENSUS PICK | Washington

Nebraska at UCLA

Nebraska football coach Matt Rhule walks the sidelines during his team's game against Maryland at SECU Stadium.

Saturday, Nov. 8

9:00 p.m. ET | Fox (Stream fuboTV (watch here))

Betting Line | UCLA -1.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | UCLA

Mark Russell (@MarkRussell1975) | Nebraska

Griffin Dreifaldt (@griffin_drei) | UCLA

Yesh Ginsburg (@yesh222) | Nebraska

CONSENSUS PICK | UCLA

Next … 5 biggest non-Big Ten games

Georgia at Mississippi State

JACKSONVILLE, FLORIDA - NOVEMBER 01: Elyiss Williams #10 of the Georgia Bulldogs carries the ball after a reception against the Florida Gators during the first quarter of the game at EverBank Stadium on November 01, 2025 in Jacksonville, Florida. (Photo by Megan Briggs/Getty Images)

Saturday, Nov. 8

Noon ET | ESPN (Stream fuboTV (watch here))

Betting Line | Georgia -8.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Georgia

Mark Russell (@MarkRussell1975) | Georgia

Griffin Dreifaldt (@griffin_drei) | Georgia*

Yesh Ginsburg (@yesh222) | Georgia*

CONSENSUS PICK | Georgia

BYU at Texas Tech

Texas Tech's Cameron Dickey runs for a touchdown against Kansas during a Big 12 Conference football game, Saturday, Oct. 11, 2025, at Jones AT&T Stadium in Lubbock.

Saturday, Nov. 8

Noon ET | ABC (Stream fuboTV (watch here))

Betting Line | Texas Tech -10

The Picks:

Phil Harrison (@PhilHarrisonBW) | Texas Tech*

Mark Russell (@MarkRussell1975) | Texas Tech*

Griffin Dreifaldt (@griffin_drei) | Texas Tech

Yesh Ginsburg (@yesh222) | Texas Tech

CONSENSUS PICK | Texas Tech

Texas A&M at Missouri

Oct 25, 2025; Baton Rouge, Louisiana, USA; Texas A&M Aggies running back Jamarion Morrow (23) celebrates with offensive lineman Chase Bisontis (71) and tight end Theo Melin Ohrstrom (17) after a touchdown during the second half against the Louisiana State Tigers at Tiger Stadium. Mandatory Credit: Stephen Lew-Imagn Images

Saturday, Nov. 8

3:30 p.m. ET | ABC (Stream fuboTV (watch here))

Betting Line | Texas A&M -7

The Picks:

Phil Harrison (@PhilHarrisonBW) | Missouri

Mark Russell (@MarkRussell1975) | Missouri

Griffin Dreifaldt (@griffin_drei) | Texas A&M*

Yesh Ginsburg (@yesh222) | Texas A&M

CONSENSUS PICK | Texas A&M

LSU at Alabama

Alabama coach Kalen DeBoer during the college football game against Tennessee at Bryant-Denny Stadium in Tuscaloosa, Ala., on Oct. 18, 2025.

Saturday, Nov. 8

7:30 p.m. ET | ABC (Stream fuboTV (watch here))

Betting Line | Alabama -10

The Picks:

Phil Harrison (@PhilHarrisonBW) | Alabama

Mark Russell (@MarkRussell1975) | Alabama

Griffin Dreifaldt (@griffin_drei) | Alabama*

Yesh Ginsburg (@yesh222) | Alabama*

CONSENSUS PICK | Alabama

Navy at Notre Dame

Notre Dame head coach Marcus Freeman celebrates a touchdown scored during the first round of the College Football Playoff between Notre Dame and Indiana University at Notre Dame Stadium on Friday, Dec. 20, 2024, in South Bend.

Saturday, Nov. 8

7:30 p.m. ET | NBC (Stream fuboTV (watch here))

Betting Line | Notre Dame -26.5

The Picks:

Phil Harrison (@PhilHarrisonBW) | Notre Dame

Mark Russell (@MarkRussell1975) | Notre Dame

Griffin Dreifaldt (@griffin_drei) | Notre Dame

Yesh Ginsburg (@yesh222) | Notre Dame*

CONSENSUS PICK | Notre Dame

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This article originally appeared on Buckeyes Wire: Big Ten and biggest college football game predictions for week 11

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