OPENING ODDS: Notre Dame is a massive road favorite against Purdue

OPENING ODDS: Notre Dame is a massive road favorite against Purdue

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OPENING ODDS: Notre Dame is a massive road favorite against Purdue
Notre Dame defensive lineman Tionne Gray (0) celebrates after getting a sack during a NCAA football game against Michigan State at Notre Dame Stadium on Saturday, Sept. 19, 2026, in South Bend. | USA TODAY Network via Reuters Co

Notre Dame is now 3-0 to start the season after its 27-10 win over the Michigan State Spartans in the Battle for the Megaphone. In that game, the Irish were nearly a 30 point favorite, and failed to cover the spread for the first time this season. Under Marcus Freeman, no school has been better against the spread than Notre Dame… so we’ll just call that game against Sparty an anomoly and move on to the Purdue Boilermakers.

According to FanDuel Sportsbook, Notre Dame is a 26.5 point favorite over Purdue with an over/under of 57.5 points.

Notre Dame is currently scoring 40 points per game while only allowing just a little over 7 points in each contest. Contrast that with Purdue, who is almost scoring 40 points a game — but giving up over 36 points on average in each game.

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