ESPN's College GameDay picks Week 6's top games

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Week 6 of the college football season is here, and ESPN's premier preview show is back to pick college football's most intriguing games.

This week, "College GameDay" was in Tuscaloosa, Alabama, for the top-25 SEC showdown between the No. 2 Georgia Bulldogs and No. 7 Alabama Crimson Tide. The University of Alabama has hosted College GameDay 21 times since the show began broadcasting live on college campuses in 1993, second only to Ohio State, which has hosted 26 times. Alabama last hosted College GameDay on Oct. 4, 2025, ahead of its 30-14 win over Vanderbilt.

This week, the usual lineup of Rece Davis, Kirk Herbstreit, Desmond Howard, Pat McAfee, and former Alabama head coach Nick Saban made their picks for this week's biggest games, with Bryce Young serving as this week's celebrity guest picker.

Young led the Crimson Tide to the College Football Playoff National Championship in 2020, and went on to win the Heisman Trophy in 2021, becoming the fourth Alabama player to win the coveted award. The Carolina Panthers drafted Young No. 1 overall in 2023, and he serves as the team's starting quarterback.

How did the College Gameday crew forecast this week's top games? Here's a look at this week's picks for Week 6 of the college football season.

LSU at Kentucky

  • Desmond Howard: LSU
  • Nick Saban: LSU
  • Pat McAfee: LSU
  • Kirk Herbstreit: LSU
  • Bryce Young: LSU

North Dakota State at UNLV

  • Desmond Howard: North Dakota State
  • Nick Saban: North Dakota State
  • Pat McAfee: North Dakota State
  • Kirk Herbstreit: North Dakota State
  • Bryce Young: North Dakota State

North Carolina at Pittsburgh

  • Desmond Howard: Pitt
  • Nick Saban: North Carolina
  • Pat McAfee: North Carolina
  • Kirk Herbstreit: North Carolina
  • Bryce Young: North Carolina

Houston at Kansas State

  • Desmond Howard: Houston
  • Nick Saban: Houston
  • Pat McAfee: Houston
  • Kirk Herbstreit: Kansas State
  • Bryce Young: Houston

Texas A&M at Missouri

  • Desmond Howard: Missouri
  • Nick Saban: Missouri
  • Pat McAfee: Missouri
  • Kirk Herbstreit: Missouri
  • Bryce Young: Texas A&M

South Carolina at Florida

  • Desmond Howard: Florida
  • Nick Saban: Florida
  • Pat McAfee: Florida
  • Kirk Herbstreit: Florida
  • Bryce Young: Florida

USC at Penn State

  • Desmond Howard: USC
  • Nick Saban: USC
  • Pat McAfee: Penn State
  • Kirk Herbstreit: USC
  • Bryce Young: USC

UCLA at Oregon

  • Desmond Howard: Oregon
  • Nick Saban: Oregon
  • Pat McAfee: Oregon
  • Kirk Herbstreit: UCLA
  • Bryce Young: UCLA

Indiana at Nebraska

  • Desmond Howard: Indiana
  • Nick Saban: Indiana
  • Pat McAfee: Indiana
  • Kirk Herbstreit: Indiana
  • Bryce Young: Indiana

Texas vs Oklahoma

  • Desmond Howard: Texas
  • Nick Saban: Texas
  • Pat McAfee: Texas
  • Kirk Herbstreit: Texas
  • Bryce Young: Texas

Alabama at Georgia

  • Desmond Howard: Alabama
  • Nick Saban: Alabama
  • Pat McAfee: Georgia
  • Kirk Herbstreit: No pick due to being on ESPN's broadcast of the game
  • Bryce Young: Alabama

Taylor Jones is the lead writer for Auburn Wire, part of the USA TODAY Network. Follow him on X (formerly Twitter) and BlueSky. Follow Auburn Wire on X and Facebook.

This article originally appeared on Auburn Wire: ESPN's College GameDay picks Week 6's top games

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