Colorado vs West Virginia Prediction: The Big 12’s Most Interesting Game
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Oklahoma State is the Big 12’s worst team, but Colorado and West Virginia are in the mix to be the 15th-best team.
The Mountaineers, though, have been far better, pushing TCU a few weeks ago before screwing up Houston’s season with a stunning 45-35 win.
This might be the end of the fun, though, with at Arizona State and Texas Tech to close, but the arrow is pointing up.
And then there’s Colorado.
After stunning Iowa State in mid-October, the wheels have come flying off the bus, losing to Utah and Arizona by a combined score of 105-24. With Kansas State and at Kansas State to close, this could get ugly without a win here.
Colorado vs West Virginia Preview
How To Watch Colorado vs West Virginia
Date: Saturday, November 8, 2025
Game Time: 12:00 PM ET
TV: TNT
Location: Milan Puskar Stadium, Morgantown, WV
@PeteFiutak
Why Colorado Will Win
Alright, let’s see what you’ve got, Julian Lewis.
Colorado desperately needs a spark. It needs something to get everyone excited for 2026, because this has turned into a humiliating disaster of a campaign.
Lewis was the big quarterback recruit for Deion Sanders, and he’s been able to get a little bit of time, but now he gets to step in and let it rip.
West Virginia might be having a few nice moments, but the pass defense isn’t stopping anything. If you’re not throwing for 300 yards against this bunch, it’s because you’re running for 200. Give Lewis time, and let’s see what he can do, but …
Why West Virginia Will Win
Colorado doesn’t have the lines.
It takes a while to build up the infrastructure, and at the moment, it’s not there. The running game hasn’t been able to do much of anything in the Big 12, and the problem for this, the run defense is being run on at will.
Utah ran for 422 yards because it didn’t feel like running for 500. Arizona and Iowa State ripped off yards in chunks, and on the year, the Buffaloes have allowed 200 yards or more six times.
West Virginia might be wildly inconsistent – it’s rebuilding – but it threw for over 300 yards against TCU, ran for 246 against Houston last week, and …
Colorado vs West Virginia Prediction, Betting Lines
Normally, this would be the week when West Virginia comes back down to earth after the wonderful performance at Houston, but Colorado has become totally inept.
The Utah game was horrendous, the big response against Arizona wasn’t there, and even though Lewis is a talent who’ll get plenty of room to make mistakes, it won’t be enough.
The Colorado defense won’t stop the Mountaineer running game even a little bit.
West Virginia 31, Colorado 24
Line: West Virginia -6.5, o/u: 53.5
ATS Confidence out of 5: 3.5
Must See Rating: 3
– CFN Week 11 Expert Picks
Consensus Line from BetMGM, Caesars, DraftKings, and FanDuel. Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.
– CFN Top 25 Rankings
Related: Kansas vs Arizona Prediction, Preview, and Betting Lines
This story was originally reported by College Football News on Nov 7, 2025, where it first appeared in the College Football section. Add College Football News as a Preferred Source by clicking here.
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